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Nanobiosensorics Laboratory

Welcome to the webpage of the Nanobiosensorics Laboratory.
Label-free methods in life sciences are on the rise. To deeply understand cellular processes at the molecular scale one needs reliable kinetic and structural data, not affected by additional labelling.
The Nanobiosensorics Laboratory focuses on the development and application of label-free optical biosensors and combine these technologies with single cell manipulation techniques.
Our research topics are ranging form the kinetics of cellular adhesion, migration and signalling on novel biomimetic interfaces to the mathematical modelling of the measured biological signals.

Label-free instrumentation

Holomonitor M4 holographic transmission microscope

Optical waveguide lightmode spectroscopy

Video about our laboratory

Our laboratory was established as an independent research group in the second half of 2012. In 2013, a cell-culture laboratory was set up to enable a start in the field of the so far not explored, unique „label-free biosensorics on living cells”. Strategically important results were achieved and published in international periodicals in several directions: measuring equipment development, monitoring of micro-vesicules secreted by the cells, the use of flagellar functional layers, and the development of theoretical models for the analysis of ordered biological layers. Some pioneering results were also achieved in the field of the investigation of ordered biological films (proteins, lipid double layers), which can be utilized for different medical diagnostic purposes.